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#Ashwagandha

Evidence-based guide to ashwagandha (Withania somnifera) — stress, sleep, recovery, contraindications and interactions.

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Ashwagandha (Withania somnifera) is the most-studied adaptogenic herb in modern supplement science. Roots have been used in Ayurveda for over 3,000 years; today's products use standardised extracts (typically KSM-66 or Sensoril).

Evidence. Small but consistent RCTs suggest ashwagandha may help modulate the stress response (lowering cortisol modestly), support sleep quality, and aid resistance-training recovery. Quality of evidence is moderate — most trials are small, short and industry-funded.

Doses. Studied protocols use 250-600 mg/day of a standardised root extract for 6-12 weeks. Higher doses (>1 g/day) raise the risk of GI side effects and have been associated with rare liver-injury case reports.

Who should avoid. People with thyroid disorders (ashwagandha may elevate T4), autoimmune conditions, hormone-sensitive cancers, and those who are pregnant or nursing. It may also interact with sedatives, immunosuppressants and thyroid medication.

Forms. KSM-66 (standardised to 5% withanolides, water-soluble) is the most-cited form for recovery and sleep. Sensoril (10% withanolides, water-and-alcohol-extracted) is more studied for anxiety and cortisol modulation.

On HealthyHerbology we cover ashwagandha across women's adaptogen and hormonal-support angles, men's testosterone-adjacent and recovery angles, and sleep-supportive supplementation.

Frequently asked about Ashwagandha

What does ashwagandha do?
Ashwagandha (Withania somnifera) is an adaptogenic herb traditionally used in Ayurveda. Modern studies suggest it may help modulate cortisol, support sleep quality and resistance-training recovery.
Who should avoid ashwagandha?
People with thyroid disorders, autoimmune conditions, hormone-sensitive cancers and those who are pregnant or nursing should avoid ashwagandha. It may also interact with sedatives and immunosuppressants.
How much ashwagandha is safe?
Studied doses typically fall between 250-600 mg/day of a standardised root extract. Higher doses (>1 g/day) raise the risk of GI side effects and have been associated with rare liver-injury case reports.
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